Thursday, February 10, 2011

Brain Tumor

This article is about brain tumors. http://www.sciencedaily.com/releases/2011/01/110124184428.htm

Gilioblastoma, is the most common and lethal form of brain cancer that is out there. This brain tumor resists all treatments when it is given to the patient. When the gilioblastoma is running out of oxygen it shifts gears and gets into the blood vessels to ensure that they continue with supply and nutrients.

The tumors can grow in one to two millimeters in diameter, about the size of a pinhead, also tumors need their own blood supply to survive. Many tumors can overexpress growth factors predomintaly vasular enothelial growth factor, also known as the VEGF. Which led to the development of Avasti, which is a monoclonal antibody that interecepts the VEGF.

They injected rats with viruses that carry out activated oncogenes and a marker gene that causes all the cells to glow green under the ultraviolet light. Its intersting to see what they can do with rats to see how it is similar in the human brain when it comes to the brain tumor.

Feel free to read more!

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